Pentobarbital will decrease the level or effect of aprepitant by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor. pentobarbital will decrease the level or effect of diclofenac by affecting hepatic enzyme CYP2C9/10 metabolism. Minor/Significance Unknown. pentobarbital will decrease the level or effect of osilodrostat by affecting hepatic/intestinal enzyme CYP... https://webookmarks.com/story5888889/pentobarbital-cosa-%C3%88-una-panoramica