Below, we show that conolidine, a pure analgesic alkaloid used in traditional Chinese medicine, targets ACKR3, thereby delivering supplemental evidence of the correlation involving ACKR3 and suffering modulation and opening alternative therapeutic avenues for the remedy of Persistent discomfort. We demonstrated that, in distinction to classical opioid receptors, ACKR3 https://rafaeljdvlb.wikibuysell.com/1567753/the_5_second_trick_for_what_is_conolidine